Immunologen arbeiten oft mit Abkürzungen und wissen nach einiger Zeit nicht mehr, was eigentlich abgekürzt wird. Die Tabelle soll da Abhilfe schaffen.
2B4 |
Ko-aktivierender Rezeptor bei NK-Zellen |
ACT1 |
Adapter für IL-17 Rezeptoren |
ADAP |
Adhesion and degranulation promoting adaptor protein |
Ag |
Antigen |
AIM2 |
Absent in melanoma 2 |
Ak |
Antikörper |
AP-1 |
Aktivatorprotein 1 |
APRIL |
A proliferation-inducing ligand |
APZ |
Antigen-präsentierende Zelle |
Ba |
Basophiler Granulozyt |
BAFF |
B-cell activating factor |
BAFFR |
BAFF Rezeptor |
BCL |
B-cell lymphoma |
BCL-10 |
B- cell lymphoma 10 |
BCMA |
B cell maturation antigen |
BLNK |
B-cell linker protein |
BTK |
Bruton’s Tyrosinkinase |
BTN3A1 |
Butyrophilin (BTN)-ähnliches Molekül |
B-Zellen |
Stammt von der Bursa fabricii der Vögel |
BZR |
B-Zell Rezeptor |
C |
Constant |
CX |
Komplementfaktor X |
C/EBPß |
CCAAT/enhancer-binding protein beta |
C1 INH |
C1 Inhibitor |
C4 BP |
C4 bindendes Protein |
CAML |
Calcium modulator and cyclophilin ligand |
cAMP |
Cyclisches AMP |
CARD |
Caspase recruitment domain-containing protein |
CARMA1 |
CARD- containing MAGUK protein 1 (= CARD11) |
CCL-19/-21 |
Chemokine (C-C motif) ligand 19/21 |
CCR |
Chemokin |
CD |
Cluster of Differentiation |
CDC42 |
Cell division control protein 42 homologue |
CIIPG |
Class II processing gene |
CIITA |
Klasse II Transaktivator |
c-KIT |
Gehört zu Rezeptor-Tyrosinkinasen; Stammzellfaktor-Rezeptor |
CLIP |
Class-II-associated invariant chain peptides |
CLP |
Common lymphoid progenitor |
c-MAF |
c-musculoaponeurotic fibrosarcoma oncogene homolog |
COPD |
Chronic obstructive pulmonary disease |
CPG-DNA |
Cytosin-Phosphat-Guanin DNA |
CR |
Komplement Rezeptor |
CRAC |
Calcium release- activated calcium channel |
CREB |
Cyclic AMP-responsive element-binding protein |
CSF |
Colonie-stimulierender Faktor |
CSF3 |
Colonie-stimulierender Faktor 3 |
CSF3R |
CSF3 Rezeptor |
cSMAC |
Central supramolecular activation complex |
CSR |
Class switch recombination |
cTEC |
Kortikale Thymus-Epithelzellen |
cTFH |
Zirkulierende follikuläre T-Zellen |
CTL |
Zytotoxischer T-Lymphozyt |
CTLA-4 |
cytotoxic T-lymphocyte antigen‑4 |
CXCL |
Chemokine (C-X-C motif) ligand |
CXCR |
CXC-Motiv-Chemokinrezeptor |
Cys |
Cystein |
D |
Diversity |
DAG |
Diacylglycerol |
DAMPs |
Danger associated molecular patterns |
DAP10 |
DNAX-activating protein 10 |
DARC |
Duffy antigen receptor for chemokines |
DHR1/2 |
DOCK Homologie Regionen 1/2 |
DM |
HLA DM |
DN |
HLA DN |
DN |
Doppelt negative T-Zellen (CD4-/CD8-) |
DNA |
Desoxyribonukleinsäure |
DO |
HLA DO |
DOCK8 |
Dedicator of cytokinesis 8 |
DP |
HLA DP |
DP |
Doppelt positive T-Zellen (CD4+/CD8+) |
DQ |
HLA DQ |
DR |
HLA DR |
dsRNA |
Doppelstrang RNA |
DZ |
Dendritische Zelle |
EBNA |
EBV nuclear antigen |
EBV |
Epstein Barr Virus |
Eos |
Eosinophiler Granulozyt |
EPCR |
Endothelial protein C receptor, MHC/CD1 verwandtes Molekül |
ER |
Endoplasmatisches Retikulum |
ERK |
Extracellular signal- regulated kinase |
ETP |
Early T cell lineage progenitor |
EVER |
Protein für Abwehr der Epidermodysplasia verruciformis im endoplasmatischen Retikulum |
ExTH17 |
Ehemalige TH17 Zelle |
Fab |
Fragment des Ig-Moleküls für Antigenbindung |
FADD |
FAS-associated death domain |
FAS |
Fas Rezeptor = CD95 = Apo-1 |
FASL |
FAS Ligand |
Fc |
Konstantes Fragment des Ig-Moleküls |
FcR |
Fc Rezeptor |
FDZ (FDC) |
Follikuläre dendritische Zellen |
FLT3 |
Fms-ähnliche Tyrosin Kinase 3 |
FOS |
Keine Abkürzung. Ist ein Transkriptionsfaktor der FOS-Proteinfamilie und ein Onkogen |
FOXO1 |
Forkhead box protein O1 |
Foxp3 |
Forkhead box P3 |
FRZ |
Fibroblastische retikuläre Zellen |
GADs |
GRB2‑related adaptor proteins |
GALT |
Gut associated lymphoid tissue |
GAS |
Gamma aktivierte Sequenzen oder IFNγ activation site |
GATA |
GATA-binding protein |
GC |
Germinalzentrum |
G-CSF |
Granulozyten Colonie-stimulierender Faktor |
G-CSFR |
G-CSF Rezeptor |
GDP |
Guanosin Diphosphat |
GEW |
Gewebszelle |
GITR |
Glucocorticoid-induced tumor necrosis factor receptor |
GM-CSF |
Granulozyten Makrophagen Colonie-stimulierender Faktor |
gp |
Glykoprotein |
GTP |
Guanosin Triphosphat |
GZ |
Germinalzentrum |
HLA |
Humanes Leukozyten Antigen |
HLX |
H2.0-like homeobox 1 |
HMB PP |
4-Hydroxy-3-methyl-but-2-enyl pyrophosphate (für Isoprenoid-Biosynthese) |
HMGB |
High mobility group protein B |
HMW |
High molecular weight |
HOCL |
Hypochlorige Säure |
HOIL-1 |
heme-oxidized IRP2 ubiquitin ligase-1, Untereinheit von LUBAC |
HOIP |
HOIL-1 Interacting Protein, Untereinheit von LUBAC |
HPV |
Humane Papillomviren |
HSC |
Hämatopoetische Stammzellen |
HSP |
Heat shock protein |
ICAM |
Interzelluläres Adhäsionsmolekül |
ICOS |
Inducible T-cell costimulator |
ICOSL |
ICOS Ligand |
IDO |
Indolamin-2,3-Dioxygenase |
IEC |
Intestinale epitheliale Zellen |
IEL |
Intraepitheliale Lymphozyten |
IFN |
Interferon |
IgA |
Immunglobulin A |
IgD |
Immunglobulin D |
IgE |
Immunglobulin E |
IgG |
Immunglobulin G |
IgM |
Immunglobulin M |
Igβ |
= CD79b |
Igα |
= CD79a |
IKK |
IκB kinase, Inhibitor of κB kinase |
IL |
Interleukin |
ILC |
Innate lymphoid cell |
IL-XR |
Rezeptor für Interleukin-X |
iNKT |
Invariant natural killer T |
InsP3 |
Inositoltriphosphat |
IP3 |
Inositol Triphosphat |
IPEX |
Immundysregulation Polyendokrinopathie Enteropathie X-linked |
IPP |
Isopentenyl pyrophosphate (für Mevalonat-Stoffwechsel) |
IRAK |
Interleukin-1 receptor-associated kinase |
IRF |
Interferon responsive (regulatory) factor |
ISG |
IFN stimulierte Gene |
ISRE |
IFN-stimulated response element |
ITAM |
Tyrosin-basierte aktivierende Motive |
ITIM |
Tyrosin-basierte inhibitorische Motive |
iTregs |
Induzierte regulatorische T-Zellen |
J |
Joining |
JAK |
Janus Kinase |
JNK |
JUN N-terminal kinase |
JUN |
Keine Abkürzung. Ist ein Transkriptionsfaktor und ein Onkogen |
KIR |
Killer-cell immunoglobulin-like receptors |
KLF2 |
Krüppel-like Factor 2, Transkriptionsfaktor |
Ku70/80 |
Keine Abkürzung. Gene: XRCC6 und XRCC5 |
LAG3 |
Lymphocyte-activation gene 3 |
LAP |
Latency-associated peptide |
LAT |
Latenzprogramm |
LAT |
Linker for activation of T cells |
LCK |
Lymphocyte-specific protein tyrosine kinase |
LEKTI |
Lympho-epithelial Kazal-type inhibitor |
LFA |
Leukozyten Funktions-Antigen |
LMP |
Latent membrane protein (von EBV) |
LPS |
Lipopolysaccharid |
LTI |
Lymphoid tissue inducer |
LUBAC |
Linear ubiquitin chain assembly complex |
LYN |
Mitglied der Src Familie von Protein Tyrosin Kinasen |
M |
Mastzelle |
Mφ |
Makrophage |
MAF |
Musculoaponeurotic fibrosarcoma oncogene homolog |
MAGT1 |
Magnesium Transporter 1 |
MAK |
Membran-Attacke Komplex |
MAL |
MYD88‑adaptor-like protein |
MALT1 |
Mucosa- associated lymphoid tissue lymphoma translocation protein 1 |
MAPK |
Mitogen-activated protein kinases |
MARCO |
Macrophage receptor with collagenous structure |
MASP |
MBL-assoziierte Serin-Protease |
MBL |
Mannose-bindendes Lektin |
MCP |
Membrane Cofactor Protein |
MDA5 |
melanoma differentiation antigen 5 |
MDSC |
Myeloid-derived suppressor cells |
MEKK |
MAP/ERK Kinase Kinase |
MHC |
Major Histocompatibitity Complex |
MICA |
MHC class I related chain A, MHC/CD1 verwandtes Molekül |
MKK |
Mitogen-aktivierte Protein Kinase Kinase, MAPK Kinase |
MPO |
Myeloperoxidase |
mRNA |
Messenger RNA |
MS |
Multiple Sklerose |
MSR1 |
Macrophage Scavenger Receptor-1 |
mTEC |
Medulläre Thymus-Epithelzellen |
MTOC |
Microtubule-organizing centre |
MUNC |
Mammalian uncoordinated |
MX1 |
Myxovirus-resistant protein 1 |
MyD88 |
Myeloid differentiation factor 88 |
NEMO |
NFκB essential modulator |
NETs |
Neutrophil extracellular traps |
NFAT |
Nuclear factor of activated T cells |
NFAT |
nuclear factor of activated T cells |
N-FK |
N-Formyl Kynurenin |
NFκB |
Nuclear Factor kappa B |
NIK |
NF-κB-inducing kinase |
NK |
Natürliche Killer-Zelle |
NKG2D |
Transmembranprotein der CD94/NKG2 Familie von Typ C Lektin-ähnlichen Rezeptoren |
NKR |
NK Rezeptor |
NKT |
NK T-Zelle |
NLR |
Nucleotide-binding oligomerization domain and leucine-rich repeat-containing receptors |
NLRC |
NLR family CARD domain-containing protein |
NLRP |
NACHT, LRR and PYD domains-containing protein, = Cryopyrin |
NO |
Stickstoffmonoxid |
NOX |
NADPH Oxidase |
NTB-A |
Ko-aktivierender Rezeptor |
nTregs |
Natürliche regulatorische T-Zellen |
OAS |
oligo adenylate synthetase, ein antiviraler Faktor |
ORAI1 |
ORAI calcium release-activated calcium modulator 1 |
OX40 |
Keine Abkürzung. = CD134, TNFRSF4. T-Zell Aktivierungsmarker |
OX40L |
OX40 Ligand |
p |
Protein |
P |
Phosphat |
PAMP |
Pathogen-Associated Molecular Pattern |
pDC |
Plasmazytoide dendritische Zelle |
PECAM |
Plättchen Endothelzellen Adhäsionsmolekül |
PGE2 |
Prostaglandin E2 |
Phox |
Phagozytenoxidase |
PI3K |
Phosphoinositid (ol)-3-Kinase |
PID |
Primärer Immundefekt |
PIP2 |
Phosphatidylinositol 4,5-Bis (di) phosphat |
PIP3 |
Phosphatidylinositol 4,5-Triphosphat |
PKC |
Proteinkinase C |
PKcs |
DNA-dependent protein kinase catalytic subunit |
PKCθ |
Proteinkinase Cθ |
Pl |
Plasmazelle |
PLC |
Phospholipase C |
PRR |
Pattern-Recognition Receptor |
PSGL |
P-Selektin Glykoprotein Ligand |
pSMAC |
Peripheral supramolecular activation complex |
PtdInsP2 |
Phosphatidylinositolbis(di)phosphat |
PU.1 |
Putative proto-oncogene Spi-1 |
RA |
Retinoic acid, Retinolsäure |
RA |
Rheumatoide Arthritis |
Rab27a |
Ras-related protein 27a |
RAC |
Ras-related C3 botulinum toxin substrate, Rac Subfamilie der Rho Familie GTPasen |
RAF |
Rapidly accelerated fibrosarcoma |
RAG |
Rekombinations-aktivierendes Gen |
RAP |
Ras-related protein |
RAS |
Keine Abkürzung. Kleine GTPase mit multiplen Funktionen |
RASGRP1 |
RAS guanyl-releasing protein 1 |
REG3γ |
Regenerating islet-derived protein 3γ |
RelA |
Untereinheit der NFκB Familie |
RelB |
Untereinheit der NFκB Familie |
RFX |
Regulatory factor X |
RFXANK |
Regulatory factor X-associated ankyrin-containing protein |
RFXAP |
Regulatory factor X-associated protein |
RhoGDI |
Rho GDP-dissociation inhibitor |
RHOH |
RAS Homolog Genfamilie H |
RIG-1 |
Retinoic acid-inducible gene I |
RIP-1 |
Receptor-interacting protein 1 |
RNA |
Ribonukleinsäure |
Rorγt |
Retinoic acid receptor-related orphan receptor gamma t |
ROS |
Reactive oxygen species |
RSS |
Rekombinations-Signalsequenzen |
RTE |
Recent thymic emigrant |
SAA |
Serum Amyloid A |
SAP |
SLAM-associated protein |
SGT-1 |
Suppressor of G2 allele of skp1 |
SHARPIN |
Shank-associated RH domain-interacting protein, Untereinheit von LUBAC |
SHM |
Somatische Hypermutation |
Skint-1 |
Butyrophilin (BTN)-ähnliches Molekül |
SLAM |
Signaling lymphocytic activation molecule |
sLex |
Sialyl Lewis X |
SLP1/2 |
Synaptotagmin-like protein 1 |
SLP76 |
SH2 domain-containing leukocyte protein of 76 kDa |
SNAP |
Synaptosomal-associated protein |
SOD |
Superoxid Dismutase |
SOS1 |
Son of sevenless homologue 1 |
SP |
Einfach positive T-Zellen (CD4+ oder CD8+) |
β2 MG |
β2 Mikroglobulin |
ssRNA |
Einzelstrang RNA |
STAT |
Signal Transducer and Activator of Transcription |
STIM1 |
Stromal interaction molecule 1 |
SYK |
Spleen tyrosine kinase |
TAB |
TAK1‑binding protein |
TACI |
Transmembrane activator and CAML interactor |
TAK |
TGFβ-activated kinase |
TAP |
Transporter associated with antigen processing |
Tbet |
T-box transcription factor |
TBK1 |
TANK-binding kinase 1 |
Tc |
Zytotoxische T-Zelle |
TCM |
T-Zellen für zentrales Memory |
Tconv |
Konventionelle T-Zellen |
TdT |
Terminal Desoxynuleotidyltransferase |
TERA- |
Effektor Memory T-Zellen |
TERA+ |
Naive Effektor T-Zellen |
TFH |
Follikuläre T Helferzelle |
TGF |
Transforming growth factor |
TH |
T Helferzelle |
TH0 |
Naive T-Zelle |
TIR |
Toll-like und Interleukin 1 Rezeptoren |
TIRAP |
TIR adaptor protein |
TLR |
Toll-like Rezeptor |
Tmem |
Memory T-Zelle |
TN |
Naive T-Zellen |
Tnaiv |
Naïve T-Zelle |
TNF |
Tumor Nekrose Faktor |
TOLL |
Keine Abkürzung. Entdeckerin meinte, dass das toll ist |
Tr |
Tryptophan |
TRAF |
TNF receptor-associated factor |
TRAM |
TRIF-related adaptor molecule |
Treg |
Regulatorische T-Zelle |
TRIF |
TIR domain-containing adaptor protein inducing IFNβ |
Trm |
Residente Memory T-Zellen |
TSCM |
Stem cell memory T |
TSLP |
Thymic stromal lymphopoietin |
TYK |
Tyrosinkinase |
TZR |
T-Zell Rezeptor |
UNC119A |
Unkoordiniertes 119 Protein, ein Chaperon |
UNC93B |
Unc-93 homolog B |
V |
Variable |
VAMP |
Vesicle-associated membrane protein |
VAV |
Rho GTPase Aktivator |
VAV |
Keine Abkürzung. Ist ein Guanin Nukleotid Austauschfaktor und Onkogen |
VCA |
Virus Capsid Antigen (von EBV) |
XLF |
XRCC4-like factor |
XRCC4 |
X-ray repair cross-complementing protein 4 |
ZAP-70 |
Zeta-assoziiertes Protein mit 70 kDa (SYK Familie Tyrosin Proteinkinase) |
Δ32-CCR5 |
CCR5 mit Deletion von 32 Basenpaaren |
α-GalCer |
a-Galaktosylceramid |