|
2B4 |
Ko-aktivierender Rezeptor bei NK-Zellen |
|
ACT1 |
Adapter für IL-17 Rezeptoren |
|
ADAP |
Adhesion and degranulation promoting adaptor protein |
|
Ag |
Antigen |
|
AIM2 |
Absent in melanoma 2 |
|
Ak |
Antikörper |
|
AP-1 |
Aktivatorprotein 1 |
|
APRIL |
A proliferation-inducing ligand |
|
APZ |
Antigen-präsentierende Zelle |
|
Ba |
Basophiler Granulozyt |
|
BAFF |
B-cell activating factor |
|
BAFFR |
BAFF Rezeptor |
|
BCL |
B-cell lymphoma |
|
BCL-10 |
B- cell lymphoma 10 |
|
BCMA |
B cell maturation antigen |
|
BLNK |
B-cell linker protein |
|
BTK |
Bruton’s Tyrosinkinase |
|
BTN3A1 |
Butyrophilin (BTN)-ähnliches Molekül |
|
B-Zellen |
Stammt von der Bursa fabricii der Vögel |
|
BZR |
B-Zell Rezeptor |
|
C |
Constant |
|
CX |
Komplementfaktor X |
|
C/EBPß |
CCAAT/enhancer-binding protein beta |
|
C1 INH |
C1 Inhibitor |
|
C4 BP |
C4 bindendes Protein |
|
CAML |
Calcium modulator and cyclophilin ligand |
|
cAMP |
Cyclisches AMP |
|
CARD |
Caspase recruitment domain-containing protein |
|
CARMA1 |
CARD- containing MAGUK protein 1 (= CARD11) |
|
CCL-19/-21 |
Chemokine (C-C motif) ligand 19/21 |
|
CCR |
Chemokin |
|
CD |
Cluster of Differentiation |
|
CDC42 |
Cell division control protein 42 homologue |
|
CIIPG |
Class II processing gene |
|
CIITA |
Klasse II Transaktivator |
|
c-KIT |
Gehört zu Rezeptor-Tyrosinkinasen; Stammzellfaktor-Rezeptor |
|
CLIP |
Class-II-associated invariant chain peptides |
|
CLP |
Common lymphoid progenitor |
|
c-MAF |
c-musculoaponeurotic fibrosarcoma oncogene homolog |
|
COPD |
Chronic obstructive pulmonary disease |
|
CPG-DNA |
Cytosin-Phosphat-Guanin DNA |
|
CR |
Komplement Rezeptor |
|
CRAC |
Calcium release- activated calcium channel |
|
CREB |
Cyclic AMP-responsive element-binding protein |
|
CSF |
Colonie-stimulierender Faktor |
|
CSF3 |
Colonie-stimulierender Faktor 3 |
|
CSF3R |
CSF3 Rezeptor |
|
cSMAC |
Central supramolecular activation complex |
|
CSR |
Class switch recombination |
|
cTEC |
Kortikale Thymus-Epithelzellen |
|
cTFH |
Zirkulierende follikuläre T-Zellen |
|
CTL |
Zytotoxischer T-Lymphozyt |
|
CTLA-4 |
cytotoxic T-lymphocyte antigen‑4 |
|
CXCL |
Chemokine (C-X-C motif) ligand |
|
CXCR |
CXC-Motiv-Chemokinrezeptor |
|
Cys |
Cystein |
|
D |
Diversity |
|
DAG |
Diacylglycerol |
|
DAMPs |
Danger associated molecular patterns |
|
DAP10 |
DNAX-activating protein 10 |
|
DARC |
Duffy antigen receptor for chemokines |
|
DHR1/2 |
DOCK Homologie Regionen 1/2 |
|
DM |
HLA DM |
|
DN |
HLA DN |
|
DN |
Doppelt negative T-Zellen (CD4-/CD8-) |
|
DNA |
Desoxyribonukleinsäure |
|
DO |
HLA DO |
|
DOCK8 |
Dedicator of cytokinesis 8 |
|
DP |
HLA DP |
|
DP |
Doppelt positive T-Zellen (CD4+/CD8+) |
|
DQ |
HLA DQ |
|
DR |
HLA DR |
|
dsRNA |
Doppelstrang RNA |
|
DZ |
Dendritische Zelle |
|
EBNA |
EBV nuclear antigen |
|
EBV |
Epstein Barr Virus |
|
Eos |
Eosinophiler Granulozyt |
|
EPCR |
Endothelial protein C receptor, MHC/CD1 verwandtes Molekül |
|
ER |
Endoplasmatisches Retikulum |
|
ERK |
Extracellular signal- regulated kinase |
|
ETP |
Early T cell lineage progenitor |
|
EVER |
Protein für Abwehr der Epidermodysplasia verruciformis im endoplasmatischen Retikulum |
|
ExTH17 |
Ehemalige TH17 Zelle |
|
Fab |
Fragment des Ig-Moleküls für Antigenbindung |
|
FADD |
FAS-associated death domain |
|
FAS |
Fas Rezeptor = CD95 = Apo-1 |
|
FASL |
FAS Ligand |
|
Fc |
Konstantes Fragment des Ig-Moleküls |
|
FcR |
Fc Rezeptor |
|
FDZ (FDC) |
Follikuläre dendritische Zellen |
|
FLT3 |
Fms-ähnliche Tyrosin Kinase 3 |
|
FOS |
Keine Abkürzung. Ist ein Transkriptionsfaktor der FOS-Proteinfamilie und ein Onkogen |
|
FOXO1 |
Forkhead box protein O1 |
|
Foxp3 |
Forkhead box P3 |
|
FRZ |
Fibroblastische retikuläre Zellen |
|
GADs |
GRB2‑related adaptor proteins |
|
GALT |
Gut associated lymphoid tissue |
|
GAS |
Gamma aktivierte Sequenzen oder IFNγ activation site |
|
GATA |
GATA-binding protein |
|
GC |
Germinalzentrum |
|
G-CSF |
Granulozyten Colonie-stimulierender Faktor |
|
G-CSFR |
G-CSF Rezeptor |
|
GDP |
Guanosin Diphosphat |
|
GEW |
Gewebszelle |
|
GITR |
Glucocorticoid-induced tumor necrosis factor receptor |
|
GM-CSF |
Granulozyten Makrophagen Colonie-stimulierender Faktor |
|
gp |
Glykoprotein |
|
GTP |
Guanosin Triphosphat |
|
GZ |
Germinalzentrum |
|
HLA |
Humanes Leukozyten Antigen |
|
HLX |
H2.0-like homeobox 1 |
|
HMB PP |
4-Hydroxy-3-methyl-but-2-enyl pyrophosphate (für Isoprenoid-Biosynthese) |
|
HMGB |
High mobility group protein B |
|
HMW |
High molecular weight |
|
HOCL |
Hypochlorige Säure |
|
HOIL-1 |
heme-oxidized IRP2 ubiquitin ligase-1, Untereinheit von LUBAC |
|
HOIP |
HOIL-1 Interacting Protein, Untereinheit von LUBAC |
|
HPV |
Humane Papillomviren |
|
HSC |
Hämatopoetische Stammzellen |
|
HSP |
Heat shock protein |
|
ICAM |
Interzelluläres Adhäsionsmolekül |
|
ICOS |
Inducible T-cell costimulator |
|
ICOSL |
ICOS Ligand |
|
IDO |
Indolamin-2,3-Dioxygenase |
|
IEC |
Intestinale epitheliale Zellen |
|
IEL |
Intraepitheliale Lymphozyten |
|
IFN |
Interferon |
|
IgA |
Immunglobulin A |
|
IgD |
Immunglobulin D |
|
IgE |
Immunglobulin E |
|
IgG |
Immunglobulin G |
|
IgM |
Immunglobulin M |
|
Igβ |
= CD79b |
|
Igα |
= CD79a |
|
IKK |
IκB kinase, Inhibitor of κB kinase |
|
IL |
Interleukin |
|
ILC |
Innate lymphoid cell |
|
IL-XR |
Rezeptor für Interleukin-X |
|
iNKT |
Invariant natural killer T |
|
InsP3 |
Inositoltriphosphat |
|
IP3 |
Inositol Triphosphat |
|
IPEX |
Immundysregulation Polyendokrinopathie Enteropathie X-linked |
|
IPP |
Isopentenyl pyrophosphate (für Mevalonat-Stoffwechsel) |
|
IRAK |
Interleukin-1 receptor-associated kinase |
|
IRF |
Interferon responsive (regulatory) factor |
|
ISG |
IFN stimulierte Gene |
|
ISRE |
IFN-stimulated response element |
|
ITAM |
Tyrosin-basierte aktivierende Motive |
|
ITIM |
Tyrosin-basierte inhibitorische Motive |
|
iTregs |
Induzierte regulatorische T-Zellen |
|
J |
Joining |
|
JAK |
Janus Kinase |
|
JNK |
JUN N-terminal kinase |
|
JUN |
Keine Abkürzung. Ist ein Transkriptionsfaktor und ein Onkogen |
|
KIR |
Killer-cell immunoglobulin-like receptors |
|
KLF2 |
Krüppel-like Factor 2, Transkriptionsfaktor |
|
Ku70/80 |
Keine Abkürzung. Gene: XRCC6 und XRCC5 |
|
LAG3 |
Lymphocyte-activation gene 3 |
|
LAP |
Latency-associated peptide |
|
LAT |
Latenzprogramm |
|
LAT |
Linker for activation of T cells |
|
LCK |
Lymphocyte-specific protein tyrosine kinase |
|
LEKTI |
Lympho-epithelial Kazal-type inhibitor |
|
LFA |
Leukozyten Funktions-Antigen |
|
LMP |
Latent membrane protein (von EBV) |
|
LPS |
Lipopolysaccharid |
|
LTI |
Lymphoid tissue inducer |
|
LUBAC |
Linear ubiquitin chain assembly complex |
|
LYN |
Mitglied der Src Familie von Protein Tyrosin Kinasen |
|
M |
Mastzelle |
|
Mφ |
Makrophage |
|
MAF |
Musculoaponeurotic fibrosarcoma oncogene homolog |
|
MAGT1 |
Magnesium Transporter 1 |
|
MAK |
Membran-Attacke Komplex |
|
MAL |
MYD88‑adaptor-like protein |
|
MALT1 |
Mucosa- associated lymphoid tissue lymphoma translocation protein 1 |
|
MAPK |
Mitogen-activated protein kinases |
|
MARCO |
Macrophage receptor with collagenous structure |
|
MASP |
MBL-assoziierte Serin-Protease |
|
MBL |
Mannose-bindendes Lektin |
|
MCP |
Membrane Cofactor Protein |
|
MDA5 |
melanoma differentiation antigen 5 |
|
MDSC |
Myeloid-derived suppressor cells |
|
MEKK |
MAP/ERK Kinase Kinase |
|
MHC |
Major Histocompatibitity Complex |
|
MICA |
MHC class I related chain A, MHC/CD1 verwandtes Molekül |
|
MKK |
Mitogen-aktivierte Protein Kinase Kinase, MAPK Kinase |
|
MPO |
Myeloperoxidase |
|
mRNA |
Messenger RNA |
|
MS |
Multiple Sklerose |
|
MSR1 |
Macrophage Scavenger Receptor-1 |
|
mTEC |
Medulläre Thymus-Epithelzellen |
|
MTOC |
Microtubule-organizing centre |
|
MUNC |
Mammalian uncoordinated |
|
MX1 |
Myxovirus-resistant protein 1 |
|
MyD88 |
Myeloid differentiation factor 88 |
|
NEMO |
NFκB essential modulator |
|
NETs |
Neutrophil extracellular traps |
|
NFAT |
Nuclear factor of activated T cells |
|
NFAT |
nuclear factor of activated T cells |
|
N-FK |
N-Formyl Kynurenin |
|
NFκB |
Nuclear Factor kappa B |
|
NIK |
NF-κB-inducing kinase |
|
NK |
Natürliche Killer-Zelle |
|
NKG2D |
Transmembranprotein der CD94/NKG2 Familie von Typ C Lektin-ähnlichen Rezeptoren |
|
NKR |
NK Rezeptor |
|
NKT |
NK T-Zelle |
|
NLR |
Nucleotide-binding oligomerization domain and leucine-rich repeat-containing receptors |
|
NLRC |
NLR family CARD domain-containing protein |
|
NLRP |
NACHT, LRR and PYD domains-containing protein, = Cryopyrin |
|
NO |
Stickstoffmonoxid |
|
NOX |
NADPH Oxidase |
|
NTB-A |
Ko-aktivierender Rezeptor |
|
nTregs |
Natürliche regulatorische T-Zellen |
|
OAS |
oligo adenylate synthetase, ein antiviraler Faktor |
|
ORAI1 |
ORAI calcium release-activated calcium modulator 1 |
|
OX40 |
Keine Abkürzung. = CD134, TNFRSF4. T-Zell Aktivierungsmarker |
|
OX40L |
OX40 Ligand |
|
p |
Protein |
|
P |
Phosphat |
|
PAMP |
Pathogen-Associated Molecular Pattern |
|
pDC |
Plasmazytoide dendritische Zelle |
|
PECAM |
Plättchen Endothelzellen Adhäsionsmolekül |
|
PGE2 |
Prostaglandin E2 |
|
Phox |
Phagozytenoxidase |
|
PI3K |
Phosphoinositid (ol)-3-Kinase |
|
PID |
Primärer Immundefekt |
|
PIP2 |
Phosphatidylinositol 4,5-Bis (di) phosphat |
|
PIP3 |
Phosphatidylinositol 4,5-Triphosphat |
|
PKC |
Proteinkinase C |
|
PKcs |
DNA-dependent protein kinase catalytic subunit |
|
PKCθ |
Proteinkinase Cθ |
|
Pl |
Plasmazelle |
|
PLC |
Phospholipase C |
|
PRR |
Pattern-Recognition Receptor |
|
PSGL |
P-Selektin Glykoprotein Ligand |
|
pSMAC |
Peripheral supramolecular activation complex |
|
PtdInsP2 |
Phosphatidylinositolbis(di)phosphat |
|
PU.1 |
Putative proto-oncogene Spi-1 |
|
RA |
Retinoic acid, Retinolsäure |
|
RA |
Rheumatoide Arthritis |
|
Rab27a |
Ras-related protein 27a |
|
RAC |
Ras-related C3 botulinum toxin substrate, Rac Subfamilie der Rho Familie GTPasen |
|
RAF |
Rapidly accelerated fibrosarcoma |
|
RAG |
Rekombinations-aktivierendes Gen |
|
RAP |
Ras-related protein |
|
RAS |
Keine Abkürzung. Kleine GTPase mit multiplen Funktionen |
|
RASGRP1 |
RAS guanyl-releasing protein 1 |
|
REG3γ |
Regenerating islet-derived protein 3γ |
|
RelA |
Untereinheit der NFκB Familie |
|
RelB |
Untereinheit der NFκB Familie |
|
RFX |
Regulatory factor X |
|
RFXANK |
Regulatory factor X-associated ankyrin-containing protein |
|
RFXAP |
Regulatory factor X-associated protein |
|
RhoGDI |
Rho GDP-dissociation inhibitor |
|
RHOH |
RAS Homolog Genfamilie H |
|
RIG-1 |
Retinoic acid-inducible gene I |
|
RIP-1 |
Receptor-interacting protein 1 |
|
RNA |
Ribonukleinsäure |
|
Rorγt |
Retinoic acid receptor-related orphan receptor gamma t |
|
ROS |
Reactive oxygen species |
|
RSS |
Rekombinations-Signalsequenzen |
|
RTE |
Recent thymic emigrant |
|
SAA |
Serum Amyloid A |
|
SAP |
SLAM-associated protein |
|
SGT-1 |
Suppressor of G2 allele of skp1 |
|
SHARPIN |
Shank-associated RH domain-interacting protein, Untereinheit von LUBAC |
|
SHM |
Somatische Hypermutation |
|
Skint-1 |
Butyrophilin (BTN)-ähnliches Molekül |
|
SLAM |
Signaling lymphocytic activation molecule |
|
sLex |
Sialyl Lewis X |
|
SLP1/2 |
Synaptotagmin-like protein 1 |
|
SLP76 |
SH2 domain-containing leukocyte protein of 76 kDa |
|
SNAP |
Synaptosomal-associated protein |
|
SOD |
Superoxid Dismutase |
|
SOS1 |
Son of sevenless homologue 1 |
|
SP |
Einfach positive T-Zellen (CD4+ oder CD8+) |
|
β2 MG |
β2 Mikroglobulin |
|
ssRNA |
Einzelstrang RNA |
|
STAT |
Signal Transducer and Activator of Transcription |
|
STIM1 |
Stromal interaction molecule 1 |
|
SYK |
Spleen tyrosine kinase |
|
TAB |
TAK1‑binding protein |
|
TACI |
Transmembrane activator and CAML interactor |
|
TAK |
TGFβ-activated kinase |
|
TAP |
Transporter associated with antigen processing |
|
Tbet |
T-box transcription factor |
|
TBK1 |
TANK-binding kinase 1 |
|
Tc |
Zytotoxische T-Zelle |
|
TCM |
T-Zellen für zentrales Memory |
|
Tconv |
Konventionelle T-Zellen |
|
TdT |
Terminal Desoxynuleotidyltransferase |
|
TERA- |
Effektor Memory T-Zellen |
|
TERA+ |
Naive Effektor T-Zellen |
|
TFH |
Follikuläre T Helferzelle |
|
TGF |
Transforming growth factor |
|
TH |
T Helferzelle |
|
TH0 |
Naive T-Zelle |
|
TIR |
Toll-like und Interleukin 1 Rezeptoren |
|
TIRAP |
TIR adaptor protein |
|
TLR |
Toll-like Rezeptor |
|
Tmem |
Memory T-Zelle |
|
TN |
Naive T-Zellen |
|
Tnaiv |
Naïve T-Zelle |
|
TNF |
Tumor Nekrose Faktor |
|
TOLL |
Keine Abkürzung. Entdeckerin meinte, dass das toll ist |
|
Tr |
Tryptophan |
|
TRAF |
TNF receptor-associated factor |
|
TRAM |
TRIF-related adaptor molecule |
|
Treg |
Regulatorische T-Zelle |
|
TRIF |
TIR domain-containing adaptor protein inducing IFNβ |
|
Trm |
Residente Memory T-Zellen |
|
TSCM |
Stem cell memory T |
|
TSLP |
Thymic stromal lymphopoietin |
|
TYK |
Tyrosinkinase |
|
TZR |
T-Zell Rezeptor |
|
UNC119A |
Unkoordiniertes 119 Protein, ein Chaperon |
|
UNC93B |
Unc-93 homolog B |
|
V |
Variable |
|
VAMP |
Vesicle-associated membrane protein |
|
VAV |
Rho GTPase Aktivator |
|
VAV |
Keine Abkürzung. Ist ein Guanin Nukleotid Austauschfaktor und Onkogen |
|
VCA |
Virus Capsid Antigen (von EBV) |
|
XLF |
XRCC4-like factor |
|
XRCC4 |
X-ray repair cross-complementing protein 4 |
|
ZAP-70 |
Zeta-assoziiertes Protein mit 70 kDa (SYK Familie Tyrosin Proteinkinase) |
|
Δ32-CCR5 |
CCR5 mit Deletion von 32 Basenpaaren |
|
α-GalCer |
a-Galaktosylceramid |
